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Gene Delivery Process Development Intern or Co-op
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Seattle, Washington
Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production
line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams
rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide
our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
Position Summary
We are seeking an enthusiastic, self-driven individual to work within the Gene Delivery Process Development team. Our team develops the end-to-end processes and technologies to
deliver the critical raw materials used in the manufacturing of engineered T cells, including viral vectors and gene editing raw materials (e.g. sgRNA, pDNA, Cas enzyme, RNPs, etc.). This team member will support process development, production, and characterization
of viral vectors and gene editing raw materials to advance our programs and platforms.
Key Responsibilities
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Design and execute hands-on experiments to develop and optimize cell and gene therapy process unit operations (e.g., suspension bioreactors, transfection, electroporation lysis, harvest/clarification, chromatography, tangiential flow filtration, etc.)
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Perform ex-vivo cell culture, including thawing, passaging, expanding, and cryopreservation of mammalian cells
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Prepare ribonucleoprotein complexes in vitro using recombinant protein and nucleic acid solutions
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Support technology development for manufacture of gene delivery raw materials
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Design and analyze lab experiments using statistical (DOE) methods and software
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Maintain proper documentation of experiments using an electronic lab notebook
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Summarize and present scientific data; communicate progress to project teams
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Maintain a safe work environment in accordance with policies, procedures, and regulations
Qualifications & Experience
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Currently working toward B.S. in Biological or Chemical Engineering, Virology, Biomedical Engineering, Chemistry, Physics, Microbiology, Molecular or Cellular Biology, or Biochemistry (graduation date December 2024 and later)
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Hands-on experience with biological laboratory procedures (ie. aseptic technique, mammalian cell culture, transfection, electroporation, filtration, ultrafiltration/diafiltration, chromatography, cryopreservation)
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Understanding of cell biology, molecular biology, and biochemistry including protein and nucleic acid structure and function
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Familiarity with analytical techniques (e.g., PCR, flow cytometry, ELISA, HPLC, etc.)
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Ability to apply scientific principles and engineering fundamentals to solve problems
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Understanding of statistical methods of experimental design and familiarity with DOE software (e.g. JMP, Minitab, R, etc.)
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Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team
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Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on the lives of patients with serious diseases
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Ability to communicate clearly and concisely through oral presentation and technical writing
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Candidate must be a US citizen, lawful permanent resident of the US, or otherwise authorized to work in the US without requiring sponsorship now or in the future
The starting compensation for this job is a range from $20.00 - $29.00/hour.
Gene
Delivery Process Development Intern or Co-op in Seattle, Washington | Bristol-Myers Squibb Co (bms.com)
Questions?
Brynn Olden, Ph.D.
Senior Principal Scientist
| Gene Delivery Process & Analytical Development
Cell Therapy Development
Brynn.Olden@bms.com
OSU Chemical Engineering alumni
Josefine Fleetwood (She/Her), Employer Relations Manager
Oregon State University | College of Engineering
School of Chemical, Biological and Environmental Engineering
School of Nuclear Science and Engineering
Department of Biological and Ecological Engineering
116 Johnson Hall - Room 112
541-737-7286
Josefine.fleetwood@oregonstate.edu